Quinoline Analogs as Antiangiogenic Agents and Telomerase Inhibitors
Identifieur interne : 001B10 ( Main/Exploration ); précédent : 001B09; suivant : 001B11Quinoline Analogs as Antiangiogenic Agents and Telomerase Inhibitors
Auteurs : Mahmud Tareq Hassan Khan [Norvège, Bangladesh]Source :
- Topics in Heterocyclic Chemistry [ 1861-9282 ]
Abstract
Abstract: Quinoline and quindoline analogs have been shown to exhibit a wide variety of pharmacological activities, including on different types of cancers. This chapter begins by reviewing some general aspects of quindoline and its analogs, including their potential pharmacological and other general uses. The chapter then details several of the latest findings on the activities of quindoline analogs against a number of specific cancers and tumor subtypes, as well as angiogenesis. Methods of synthesizing several of these analogs, which were proposed by subsequent authors, are also discussed.
Url:
DOI: 10.1007/7081_2007_087
Affiliations:
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<front><div type="abstract" xml:lang="en">Abstract: Quinoline and quindoline analogs have been shown to exhibit a wide variety of pharmacological activities, including on different types of cancers. This chapter begins by reviewing some general aspects of quindoline and its analogs, including their potential pharmacological and other general uses. The chapter then details several of the latest findings on the activities of quindoline analogs against a number of specific cancers and tumor subtypes, as well as angiogenesis. Methods of synthesizing several of these analogs, which were proposed by subsequent authors, are also discussed.</div>
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